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News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… Jeannine Mjoseth … For the first time, National Institutes of Health (NIH) researchers have demonstrated in mice that gene therapy may be the best method for correcting the single … M.D., Ph.D., senior investigator in the NHGRI Medical Genomics and Metabolic Genetics Branch. "For NPC1 patients, …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… Raymond MacDougall … National Institutes of Health researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare … are small, non-coding RNA molecules involved in the regulation of gene expression. When the AAV was inserted near …
News Release
NIH researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate.
… disorder. … Researchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
… Advances in genomics are helping you access information about your genome … was valued at $117 million in 2017, suggesting millions of people are purchasing these tests. In contrast to clinical … science behind the claim that certain variants in the gene ACTN3 control different types of muscle fibers …
Fact Sheets
Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.
… Genomics is the study of all of a person's genes (the genome), including … the information needed to build the entire human body. A gene traditionally refers to the unit of DNA that carries the … for medical science? … Related Contents … A Brief Guide to Genomics … Genomics is the study of all of a person's genes …
Fact Sheet
Understanding gene therapy for sickle cell disease
… than 100,000 people. … Presently, there are only a handful of options to manage or treat sickle cell disease. Now, researchers are developing new and emerging gene therapies to treat sickle cell disease. To help navigate … and individuals. This group met over the course of four workshops. … The Democratizing Education Project …
Community Outreach
NHGRI is proud to help support the PBS documentary, “Ken Burns presents The Gene: An Intimate History,” based on the book by Siddhartha Mukherjee, M.D.
… help support the PBS documentary, “Ken Burns presents The Gene: An Intimate History,” based on the book by Siddhartha … a journey through key genetics discoveries that are some of the greatest achievements in the history of science. … In this fun animated series, the gene’s complex …
Talking Glossary
Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs.
… racism. Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs. … racism. Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs. … in the 19th and early 20th centuries were proponents of such ideologies. By the mid-20th century, …
News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has … from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that … Michael Snyder, Ph.D., director, Stanford Center for Genomics and Personalized Medicine, Stanford University, …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… Gene Therapy … Gene therapy is an experimental technique for … disorder. Often, gene therapy works by adding new copies of a gene that is broken, or by replacing a defective or … missing gene in a patient’s cells with a healthy version of that gene. Both inherited genetic diseases (e.g., …