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Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… population genomics research can be used to study human ancestry, migrations and health. … Population genomics is the …
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… an approach that oversimplifies the complex interplay of ancestry, health, disease and drug response. … In a May 26 …
Genomics 101
Find out how the rapidly emerging field of genomics is transforming our understanding of human health and enabling advances that benefit all of humankind.
… genome contains many important clues about you—from your ancestry to the way your body responds to diseases, …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
…  … Polygenic scoring accuracy varies across the genetic ancestry continuum Ding et al. Nature . 2023 … that involve data generated from individuals of European ancestry, but such studies are limited in their applicability …
News Release
NHGRI hosts a Reddit "Ask Me Anything" about using virtual reality to study a host of questions about the human genome.
… a recent analysis found that individuals of European ancestry make up the vast majority of the participants in …
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
… or fat-like substance in the blood) in people of African ancestry. The researchers investigated whether smoking … a concerted effort to include many people of non-European ancestry since there are too few genomics studies of diverse … of lipids in terms of number of participants with African ancestry. This enabled researchers to find new gene regions …
Event
The NHGRI and NCI held a pre-application webinar on May 15, 2020, for the Funding Opportunity Announcements (FOA) RFA-HG-20-001 and RFA-HG-20-002.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites and Coordinating Center (U01 Clinical …
Research at NHGRI
CRGGH uses genomic tools to understand the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney disease.
… Partial Test. Hum Hered, 73:73-83. 2012. [ PubMed ] Ancestry Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN. … reconstruction of the 140,000 year history of modern human ancestry. Sci Rep 4:6055. 2014. [ PubMed ] Ancestry_2014.bed Ancestry_2014.bim Ancestry_2014.fam …
FAQ
On November 8-9, 2023, NHGRI sponsored its 15th Genomic Medicine meeting, Genomic Medicine XV: Genomics and Population Screening, in Bethesda MD. The following questions were answered during the meeting.
… ramifications of screening based on race and/or genetic ancestry? Recognizing that genetic variants track imperfectly … with self-identified race or background genetic ancestry, screening based on these factors will inevitably … of how people ascribe that have nothing to do with genetic ancestry and thus the two can't be conflated - …
Event
Several NIH Institutes, Offices and Centers are partnering to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data.