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Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… molecule found in bacteria and other cells. … Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA …
Educational Resources
A vector is any vehicle, often a virus or a plasmid that is used to ferry a desired DNA sequence into a host cell as part of a molecular cloning procedure.
… Acid (DNA), Cloning, Virus, Plasmid, Yeast Artificial Chromosome (YAC), Genetic Engineering … A vector, as related …
15 Ways Genomics Influences Our World
Genomics is establishing more robust methods for DNA-based forensic analyses.
… often include markers from mitochondrial DNA and the Y chromosome. Children only inherit mitochondrial DNA from their mother, and sons only inherit the Y chromosome from their father. One example of the use of … Human Identification, Missing Persons, Crime Scenes, Y Chromosome, Mitochondrial DNA, DNA-Based Predictions … …
Genetic Disorders
Factor V Leiden thrombophilia is an inherited disorder of blood clotting.
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… reported the first gapless sequence of the human X chromosome, the first truly complete human chromosome sequence. The study, published in the journal … comparisons NHGRI researchers generate complete human X chromosome sequence NHGRI-funded project creates encyclopedia …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
… histone is a protein that provides structural support to a chromosome. … Histones, DNA, Chromatin, Double Helix, Gene … is a protein that provides structural support for a chromosome. Each chromosome contains a long molecule of DNA, which must fit …
Educational Resources
In situ hybridization is a laboratory technique in which a single-stranded DNA or RNA sequence called a probe is allowed to form complementary base pairs with DNA or RNA present in a tissue or chromosome sample.
… base pairs with DNA or RNA present in a tissue or chromosome sample. … In Situ Hybridization, DNA, RNA, …
The Genomics Landscape
In the September 2023 edition of The Genomics Landscape, NHGRI Director Eric Green, recaps the April 2023 virtual reunion of the leaders of the five genome-sequencing centers (G5), where they tell the untold story on how they ushered the Human Genome Project across the finish line in 2003.
… of the first truly complete sequence of a human Y chromosome. While scientists completed ‘telomere-to-telomere’ … 23 human chromosomes last year, more than 50% of the Y chromosome’s sequence remained unknown. With this newly … finding previously unidentified genomic variants on the Y chromosome and, by studying these variants, will be better …
Clinical Studies
The IDENTIFY Study is a study exploring how prenatal blood test results for the baby might also detect cancer in the mother.
… MRI is routinely used in pregnancy to evaluate for fetal abnormalities or to answer clinical questions. There are no …
Genetic Disorders
Inborn errors of metabolism are disorders that cause a block in a metabolic pathway leading to clinically significant consequences.
… These are different in men and women: men have only one X chromosome and therefore only one copy of the genes on that chromosome, while women have two X chromosomes and therefore … ammonia, abnormal liver function tests, and blood cell abnormalities. Certain patients may also have neurologic …