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Implementing Genomics in Practice (IGNITE)



Findings from the genomics field have slowly started to find applications in clinical care. The field of "genomic medicine" could potentially improve patient health and treatment strategies or better predict the likelihood of disease.

The Implementing Genomics in Practice (IGNITE) consortium (RFA-HG-12-006, RFA-HG-12-007 and RFA-HG-13-004) was created to enhance the use of genomic medicine by supporting the development of methods for incorporating genomic information into clinical care and exploration of the methods for effective implementation, diffusion and sustainability in diverse clinical settings. 

These demonstration projects will incorporate genomic information into the electronic medical record (EMR) and provide clinical decision support (CDS) for implementation of appropriate interventions or clinical advice. The sites will work together to develop new methods and projects and disseminate their findings to the public. Dissemination of these methods and developing best practices for implementation is a key goal so that the information generated from the program will contribute to the growing knowledge base of using genomic information in patient care.

IGNITE Investigators

Study Investigators
  • Genomic Diagnosis and Personalized Therapy for Highly Penetrant Genetic Diabetes
    Principal Investigator: Toni Pollin, Ph.D., University of Maryland 
  • Genomic Medicine Implementation: The Personalized Medicine Program (PMP)
    Principal Investigator: Julie Johnson, Pharm.D., University of Florida

  • Indiana GENomics Implementation, an Opportunity for the UnderServed (INGENIOUS)
    Principal Investigator: Todd Skaar, Ph.D., Indiana University
    Co-PI: Paul Dexter, M.D., Indiana University
  • Genetic testing to Understand and Address Renal Disease Disparities (The GUARDD Study)
    Principal Investigator: Carol Horowitz, M.P.H., M.D., Mount Sinai School of Medicine

  • Implementation, Adoption, and Utility of Family History in Diverse Care Settings
    Principal Investigator: Geoffrey Ginsburg, M.D., Ph.D., Duke University
    Co-PI: Lori Orlando, M.H.S., M.D., Duke University

  • Integrated, Individuals, Intelligent Prescribing (I3P)
    Principal Investigator: Joshua Denny, M.D., Vanderbilt University
    Co-PI: Mia Levy, M.D., Ph.D., Vanderbilt University

IGNITE Network Site Locations

IGNITE Sites on U.S. Map

Project Website at the University of Florida

Meetings and Workshops

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Last Updated: July 21, 2016