Search Results
Funding Opportunities
Funding for New and Early-Stage Investigators
… One essential element of the NHGRI mission is supporting researchers through their … to make the next scientific breakthroughs in the field of genomics. NHGRI welcomes applications from new and … sciences; genomic medicine; genomic data science; and ethical, legal and social implications of genomics. Next …
Fact Sheet
Genomic data science is a field of study that enables researchers to use powerful computational and statistical methods to decode the functional information hidden in DNA sequences.
… The Big Picture Genomic data science is a field of study that enables researchers to use powerful … genomics research will generate between 2 and 40 exabytes of data within the next decade.  Our ability to sequence DNA …  Performing genomic data science carries with it a set of ethical responsibilities, as each person's sequence data are …
Policy Issues
Revisions to the Common Rule modernize, simplify, and enhance oversight for human subjects research in the United States.
… The final version of the Common Rule was published in the Federal Register on … the U.S. given that local IRBs will have more insight into ethical issues that require consideration (.114). Enforced … clinical trials are subject to the Common Rule. Standards and Tools The NPRM proposed a number of additional …
About Genomics
Appropriate use of population descriptors in scientific research is critical for the advancement of genomic science and human health for all.Â
…  In response to a request from the National Institutes of Health, the National Academies assembled an interdisciplinary committee of expert volunteers to conduct a study to review and assess existing methodologies, …
The Genomics Landscape
In the December 2018 edition of The Genomics Landscape, NHGRI Director Eric Green recaps progress from NHGRI strategic planning process events in 2018.
… Eric Green, M.D., Ph.D. … As signaled by the rapid arrival of cold weather and the seemingly overnight arrival of holiday-themed daily life, the year 2018 is rapidly coming … to gather input from focused groups, such as experts in ethical, legal, and social implications (ELSI) research. In …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… January 13, 2022  Data sharing is central to the field of genomics. Both human and non-human genomic data have been … information about the data), using commonly accepted data standards, submitting to a FAIR data repository, and working … funding describe the data they plan to share and the data standards they plan to use. In addition, the draft …
Health
Genomic medicine involves using genomic information as part of clinical care and the health outcomes and policy implications of that clinical use.
… using genomic information about an individual as part of their clinical care (e.g. for diagnostic or therapeutic … or "clinical utility," professional societies and clinical standards groups will use that evidence to determine whether … This determination will also factor in any potential ethical and legal issues, as well economic factors such as …
Educational Resources
Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules based on their size and electrical charge.
… move faster than larger molecules. To determine the size of the molecules in a sample, standards of known sizes are separated on the same gel and then …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… group that was so popular it landed on the front page of Reddit, reaching a total of 10.5 million people worldwide! … From TheseanSolution I teach high school biology. Our standards are leaning more into molecular biology and there … We talk about CRISPR and genetic engineering, but don't conduct labs associated with the concepts. Is the CRISPR …
Talking Glossary
The genome reference sequence provides a general framework and is not the DNA sequence of a single person.
… provides a general framework and is not the DNA sequence of a single person. … A human genome reference sequence is an accepted representation of the human genome sequence that is used by researchers as a … highest-quality, best possible consensus representations of the sequence and structural diversity found in the human …