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$1,000 Genome Program

Driving down the cost of sequencing by developing new methods.


In 2004, NHGRI initiated a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in biomedical research and health care. Some of the successes of this program, which culminated in 2014, are described in Nature: “Technology: The $1,000 Genome.” The history and achievements of the $1,000 Genome Program, which was led by Dr. Jeffery Schloss, as the Sequencing Technology Development Program Director at NHGRI, are further highlighted below.

Setting the Stage

Below are program reports from workshops leading up to the start of the $1,000 Genome Program.

The concept papers linked below were discussed at the May 2003 meeting of the National Advisory Council for Human Genome Research (NACHGR). Describing future plans for NHGRI’s Sequencing Technology Development Program, the concept papers paved the way for some of the first Funding Opportunity Announcements of the $1,000 Genome Program in early 2004.

Publications and Patents

In the document linked below, listed by Principal Investigator, are citations and links to many of the articles and patents resulting from the $1,000 Genome Program and closely related research from 2004 to 2014.

$1000 Genome effort Publications and Patents

Last updated: March 25, 2022