Program Director Genome Sciences

Division of Genome Sciences


Ph.D. Case Western Reserve University, 2005


Lisa Helbling Chadwick, Ph.D. joined the National Human Genome Research Institute's Extramural Research Program as a program director in 2018. She oversees the Centers for Mendelian Genomics within the NHGRI Genome Sequencing Program.

Prior to joining NHGRI, Dr. Chadwick was a program director in the Division of Extramural Research and Training at the National Institute of Environmental Health Sciences (NIEHS), where she was involved in the leadership of the NIH Roadmap Epigenomics Program, and the NIH 4D Nucleome Program.

Dr. Chadwick received a B.A. in biology from Case Western Reserve University, a Ph.D. in genetics from Case Western Reserve University, and completed postdoctoral research at NIEHS.


Wang T, Pehrsson EC, Purushotham D, Li D, Zhuo X, Zhang B et al. (TaRGET II Consortium) The NIEHS TaRGET II Consortium and environmental epigenomics. Nat Biotechnol, 36(3):225-27. doi: 10.1038/nbt.4099. 2018.

Roadmap Epigenomics Consortium et al. Integrative analysis of 111 reference human epigenomes. Nature, 518(7539):317-30. doi: 10.1038/nature14248. 2015.

Satterlee JS, Beckel-Mitchener A, McAllister K, Procaccini DC, Rutter JL, Tyson FL, Chadwick LH. Community resources and technologies developed through the NIH Roadmap Epigenomics Program. Methods Mol Biol, 1238:27-49. doi: 10.1007/978-1-4939-1804-1_2. 2015.

Chadwick LH. The NIH Roadmap Epigenomics Program data resource. Epigenomics, 4(3):317-24. doi: 10.2217/epi.12.18. 2012.

Chadwick LH, Chadwick BP, Jaye DL, Wade PA. The Mi-2/NuRD complex associates with pericentromeric heterochromatin in rapidly proliferating lymphoid cells. Chromosoma, 118(4):445-57. doi: 10.1007/s00412-009-0207-7. 2009.

Chadwick LH, Pertz LM, Broman KW, Bartolomei MS, Willard HF. Genetic control of X chromosome inactivation in mice: definition of the Xce candidate interval. Genetics, 173(4):2103-10. 2006.

Chadwick LH and Willard HF. Genetic and parent-of-origin influences on X chromosome choice in Xce heterozygous mice. Mamm Genome, 16(9):691-9. 2005.