Bethesda, Md., Wed., Mar. 4, 2015 - New findings, reported online March 2, 2015 in the journal Nature Genetics, provide new insights into the effects and roles of genetic variation and parental influence on gene activity in mice and humans, as well as the cause of complex traits and disease in both species. Read more
Nearly 20 papers published online in 2014 highlight research on the use of DNA biorepositories and electronic medical records (EMRs) to understand the underlying genomics of disease. The papers appeared in Frontiers in Geneticsand were co-authored by members of the Electronic Medical Records and Genomics (eMERGE) Network, which is supported by NHGRI. Read more
Ribonucleic acid (RNA) transmits genetic information from DNA to the cell's protein-producing machinery. RNAs adopt specific physical structures to control when genes are turned on and off. Scientists have now devised a way to view RNA structures in living cells. The new approach, developed at Stanford University with NHGRI support, may greatly improve understanding of gene regulation in biology and medicine.
Read the paper: Structural imprints in vivo decode RNA regulatory mechanisms. Nature, March 18, 2015.
Researchers have linked multiple new regions of the human genome to body mass index (BMI) and fat distribution, according to two studies just published in Nature. Population Architecture using Genomics and Epidemiology Consortium scientists supported by the National Human Genome Research Institute contributed to the studies that may lead to more effective therapeutic targets. Read more at nature.com:
Last Updated: March 20, 2015
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