Division of Genome Sciences

The Division of Genome Sciences supports and accelerates foundational resources, technology development, experimental approaches, in basic genomics and functional genomics research. The Division also oversees a number of transformational initiatives and programs in genomic sciences.

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Overview
Research Programs
Additional Programs
Unsolicited, Investigator-Initiated Research
Funding Opportunities

Meetings and Workshops
Division Staff
Related Resources

Overview

The division supports and accelerates foundational resources, technology development, experimental approaches, data science and analytical tools that transform genome science to facilitate research on the function of the genome in human health and disease. In conducting its mission, the division also:

Assesses the need for research and research training in genome sciences and related areas.
Determines program priorities in genome sciences and related areas and recommends funding levels.
Prepares reports and analyses to assist institute staff and advisory groups in carrying out their responsibilities.
Collaborates with the other NHGRI extramural research divisions to establish a balance of resources, personnel, and research and training budgets to achieve NHGRI goals.
Provides expert advice to the director of NHGRI on various aspects of genome sciences.
Collaborates with the other NHGRI divisions, other National Institutes of Health Institutes and Centers, and other agencies and entities, nationally and internationally.
Maintains an awareness of research efforts in relevant program areas.

Overview
The division supports and accelerates foundational resources, technology development, experimental approaches, data science and analytical tools that transform genome science to facilitate research on the function of the genome in human health and disease. In conducting its mission, the division also:
Assesses the need for research and research training in genome sciences and related areas.
Determines program priorities in genome sciences and related areas and recommends funding levels.
Prepares reports and analyses to assist institute staff and advisory groups in carrying out their responsibilities.
Collaborates with the other NHGRI extramural research divisions to establish a balance of resources, personnel, and research and training budgets to achieve NHGRI goals.
Provides expert advice to the director of NHGRI on various aspects of genome sciences.
Collaborates with the other NHGRI divisions, other National Institutes of Health Institutes and Centers, and other agencies and entities, nationally and internationally.
Maintains an awareness of research efforts in relevant program areas.

Research Programs

Centers of Excellence in Genomic Science (CEGS)

Genome Technology Program

Developmental Genotype-Tissue Expression (dGTEx)

Genetic Architecture of Complex Traits

Human Genome Reference Program

Impact of Genomic Variation on Function (IGVF) Consortium

Molecular Phenotypes of Null Alleles in Cells (MorPhiC)

Funding for New and Early-Stage Investigators

The GREGoR Consortium

The Encyclopedia of DNA Elements (ENCODE)

Knockout Mouse Phenotyping Project (KOMP2)

Additional Programs

NIH Common Fund

U.S. National Science Foundation

Archived Programs

Unsolicited, Investigator-Initiated Research

NHGRI strongly supports unsolicited, investigator-initiated research, which are funded under NIH-wide “parent” Program Announcements (PAs), as well as PAs or PARs targeting specific scientific topics. Investigator-initiated means you create an application in any area of science NIH supports.

To learn more about the research areas we support and the appropriate contacts, please visit the Content Map for Contacts by Research Area or the Contacts by Research Area: Search.

For more information, please visit NHGRI's Research Funding.

Funding Opportunities

Advancing Genomic Technology Development for Research and Clinical Application (NOSI)
NOT-HG-24-012
Expiration Date: January 10, 2027
Developing Novel Theory and Methods for Understanding the Genetic Architecture of Complex Human Traits (R01 Clinical Trial Not Allowed)
PAR-25-255
Application Due Dates: Standard Dates
Expiration Date: November 6, 2026
Developing Novel Theory and Methods for Understanding the Genetic Architecture of Complex Human Traits (R21 Clinical Trial Not Allowed)
PAR-25-256
Application Due Dates: Standard Dates
Expiration Date: January 8, 2027
Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed)
RFA-HG-23-026
Application Due Dates: March 3, 2025
Expiration Date: March 4, 2025
Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
PAR-23-098
Application Receipt Date(s): June 23, 2025
Expiration Date: June 24, 2025