Last updated: May 03, 2017
Genomic Medicine X
Research Directions in Pharmacogenomics Implementation
On May 2-3, 2017, the National Human Genome Research Institute (NHGRI) sponsored its 10th Genomic Medicine meeting - Genomic Medicine X: Research Directions in Pharmacogenomics Implementation - at the Sheraton Silver Spring Hotel in Silver Spring, Maryland.
The objectives of the meeting were to:
- Survey national landscape of research programs in pharmacogenomics implementation
- Review current advances and clinical applications of pharmacogenomics
- Discuss limitations and obstacles in pharmacogenomics clinical implementation
- Identify evidence gaps and studies that are needed to address them
- Design strategies for large-scale evaluation and implementation of pharmacogenomics in clinical care in the United States.
Summaries
Tweets from the meeting: #GenomicMed10
GOLDILOKs Study: Patient Booklet
Tuesday, May 2, 2017
| Time | Topic | Speaker |
|---|---|---|
| 8:00 a.m. | Breakfast | |
| 8:30 a.m. | Welcome, Opening Remarks, General Updates | Teri Manolio NIH/NHGRI |
| 8:45 a.m. | Announcements, Opening Remarks Video - Slides |
Mary Relling (Organizing Committee Chair) St. Jude Children's Research Hospital |
| Session 1: The PGx Landscape - Overview of Ongoing Projects; Success Stories and Lessons Learned Moderator: Howard Jacob HudsonAlpha Institute for Biotechnology |
||
| 9:00 a.m. | Angela's Story - Why Pharmacogenetics Matters Video - Slides |
Guest Speaker: Paul Anderson |
| 9:20 a.m. | Exploiting Pharmacogenetic Discovery to Improve Patient Care: Why Aren't We There Yet? Video - Slides |
Keynote Speaker: Dan Roden Vanderbilt University |
| 9:50 a.m. | NIH Supported PGx Research Video - Slides |
Simona Volpi |
| 10:10 a.m. | Discussion on Session 1 Video |
|
| 10:20 a.m. | Break | |
| Session 2: Resources for PGx Implementation Moderator: Geoff Ginsburg Duke University |
||
| 10:40 a.m. | CPIC, Clinical Pharmacogenetics Implementation Consortium and PharmGKB Video - Slides |
Mary Relling St. Jude Children's Research Hospital |
| 11:00 a.m. | ClinGen, Clinical Genome Resource and ClinVar, Clinical Variant Resource Video - Slides |
Heidi Rehm ClinGen-Partners |
| 11:20 a.m. | DiGITizE, Displaying and Integrating Genetic Information Through the EHR Video - Slides |
Sandy Aronson Partners |
| 11:40 a.m. | PharmCAT, Pharmacogenomic Clinical Annotation Tool Video - Slides |
Marylyn Ritchie |
| 12:00 p.m. | Discussion on Session 2 Video |
|
| 1:00 p.m. | Working Lunch | |
| Session 3: Implementation Research Projects Moderator: Marc Williams Geisinger Health System |
||
| 1:30 p.m. | Exceptional Responders Study Video - Slides |
Nikhil Wagle Dana-Farber Cancer Institute |
| 1:50 p.m. | INdiana GENomics Implementation: an Opportunity for the UnderServed Video - Slides |
Todd Skaar Indiana University |
| 2:10 p.m. | PGx Implementation Research Programs at Northwestern Video - Slides |
Minoli Perera Northwestern |
| 2:30 p.m. | PGx Implementation at Mission Health System Video - Slides |
Lynn Dressler Mission Health System |
| 2:50 p.m. | PGx Implementation Research Programs at Vanderbilt Video - Slides |
Josh Denny Vanderbilt University |
| 3:10 p.m. | Discussion on Session 3 Video |
|
| 4:10 p.m. | Break | |
| 4:30 p.m. |
Panel Discussion: Research Gaps to be Addressed Dick Weinshilboum - Mayo Clinic |
Moderator: Rex Chisholm Northwestern University |
| 6:00 p.m. | Meeting Adjourn | |
Wednesday, May 3, 2017
| Time | Topic | Speaker |
|---|---|---|
| 8:00 a.m. | Breakfast | |
| Session 4: Evaluating Outcomes and Cost-effectiveness Moderator: Patricia Deverka American Institutes for Research |
||
| 8:30 a.m. | eMERGE-PGx Video - Slides |
Laura Rasmussen-Torvik Northwestern University |
| 8:50 a.m. | Addressing Knowledge Deficits in Pediatric PGx: The GOLDILOKs Initiative at Children's Mercy Hospital Video - Slides |
Steve Leeder Children's Mercy Kansas City |
| 9:10 a.m. | Clopidogrel Video - Slides |
Larisa Cavallari University of Florida |
| 9:30 a.m. | Pragmatic Application of Economic and Cost-effectiveness Analysis: Examples from Genomic Medicine Implementation Projects Video - Slides |
Marc Williams Geisinger Health System |
| 9:50 a.m. | Discussion for Session 4 Video |
|
| 10:50 a.m. | Break | |
| Session 5: Multidisciplinary Approaches and Training PGx Practitioners Moderator: Carol Bult The Jackson Laboratory |
||
| 11:10 a.m. | Multidisciplinary Approaches and Training PGx Practitioners at the University of Florida Video - Slides |
Kristin Weitzel University of Florida |
| 11:30 a.m. | The Inter-Society Coordinating Committee (ISCC) and Training PGx Practitioners Video - Slides |
Robert Wildin NIH/NHGRI |
| 11:50 a.m. | Multidisciplinary Approaches and Training PGx Practitioners at Moffitt Video - Slides |
Howard McLeod |
| 12:10 p.m. | Pick up Lunch & Return to Session | |
| 12:30 p.m. | Discussion for Session 5 Video |
|
| Session 6: Role of NHGRI and the Genomic Medicine Community in PGx Implementation Research Moderator: Laura Rodriguez NIH/NHGRI |
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| 1:30 p.m. | Summary and Synthesis Video - Slides |
Teri Manolio NIH/NHGRI Mary Relling St. Jude Children's Research Hospital |
| 2:30 p.m. | Next Steps | |
| 3:00 p.m. | Meeting Adjourn | |