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Research at NHGRI

The Division of Intramural Research conducts a broad program of laboratory and clinical research

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An Overview

Division of Intramural Research mission, vision and values
Buildings on NIH Main Campus


Descriptions for the nine research branches of the Division of Intramural Research
Dan Kastner

Research Investigators

Profiles of NHGRI scientists, their research and current publications
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Clinical Research

NHGRI's clinical research program, the Undiagnosed Diseases Program and current clinical studies

NHGRI Affiliated Centers

Collaborations with other NIH centers involved in genomic research
Letters A-C-T-G

Online Research Resources

Databases, software and research tools developed by NHGRI researchers
Paper Calendar

Intramural Calendar

Intramural research workshops, conferences, seminar series and courses
Books (Hard Copies)

Publications, Books, and Resources

Current publications for intramural research scientists
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Organizational Chart

Organization and personnel for the Division of Intramural Research


The 2018 Jeffrey M. Trent Lectureship in Cancer Research

Hospital CorridorThe National Human Genome Research Institute's Division of Intramural Research will present the 14th Jeffrey M. Trent Lecture in Cancer Research on March 15, 2018, 12:00 - 1:00 p.m., at the Lipsett Amphitheater, Building 10 (Clinical Center), on the National Institutes of Health (NIH) Bethesda campus. Joan Brugge, Ph.D., co-director, Ludwig Center at Harvard Medical School, will deliver the lecture Role of the TRPA1 Ca2+-permeable Channel in Oxidative Stress Defenses in Cancer.

Antibiotic-resistant plasmids flourish in hospital plumbing

Hospital CorridorAntibiotic-resistant organisms can be found on hospital countertops, doorknobs, computers, sinks and even inside the plumbing. Investigators at the National Institutes of Health (NIH) recently conducted whole genome sequencing on samples from pipes beneath the NIH Clinical Center. The majority of samples from pipes and sewers tested positive for bacterial plasmids that confer resistance to carbapenems, the "last-resort" antibiotics given to hospital patients who develop infections from pathogens that are multidrug-resistant. The study was published Feb. 6, 2018 in mBio.

Researchers study mothers' food choices at virtual reality buffet

Food BuffetMany Americans love all-you-can-eat buffets but how do they choose what to eat? Using a virtual reality (VR) buffet, NHGRI researchers studied the hundreds of micro-decisions mothers make while selecting food for their children to better understand the mechanism through which some made healthier choices. Eventually, researchers may be able to design better interventions to improve people's food choice behavior and "nudge" people toward more healthy choices.

Study: Sharing genomic results online works well for many, reduces health care costs

Man participating in online genetic counseling The cost of sequencing a person's genome has fallen has fallen considerably in the past 25 years. However, the cost of communicating genome results to patients is still sky-high, relying as it does on one-on-one counseling. In a new study, National Human Genome Research Institute researchers determined that sharing some types of genomic results online works well and could reduce health care costs. The next research question? Finding those for whom online sharing of genomic results doesn't work and ensuring they get in-person services.