Cancer patients were a little more likely to survive for five years or more after chemotherapy if they interacted during chemotherapy with other patients who also survived for five years or more, according to a new study by researchers at the National Human Genome Research Institute, part of the National Institutes of Health, and the University of Oxford in the United Kingdom. The findings were published online July 12, 2017, in the journal Network Science.
An international team of researchers has identified the genomic mutations for Carey-Fineman-Ziter (CFZS) syndrome, a very rare, inherited muscle disorder. Their findings provide insight into the development of an embryo's muscles and the regeneration of muscle cells after injury. The study was published today July 6, 2017 in Nature Communications.
A new study highlights how genomic mutations that cause mitochondrial disease may also compromise affected people's immune response. Based on clinical data from patients with mitochondrial disease, the researchers created a mouse model of mitochondrial disease in T-cells, which play important roles in humans' immune response. The mutations resulted in an increased risk of infections and reduced protective immunity after vaccinations. The study appeared June 6, 2017, in the journal Cell Metabolism.
Since 2014, NIH has offered Institutional Review Board (IRB) training to American Indians and Alaska Natives. Dr. Deana Around Him, a citizen of Cherokee Nation of Oklahoma and training participant, learned how NIH ensures the welfare of people who participate in biomedical studies and helped improve the IRB training.