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NIH

Genome Technology Program

Illumina HiSeq Flow Cell

 

Genome Technology Program Overview

The Genome Technology program supports research to develop new methods, technologies and instruments that enable rapid, low-cost determination of DNA sequence, SNP genotyping (with the Genetic Variation Program) and functional genomics (broadly defined) experiments (with the Functional Analysis Program). Priorities include the refinement of current technologies to increase efficiency and decrease cost while maintaining or improving data quality, and the development of completely novel approaches to achieve orders-of-magnitude improvement. Integration of process steps is key to achieving these goals.

The program also supports and coordinates transfer of technology from developers to users, and promotes collaborative, multidisciplinary programs that closely integrate research projects at academic and industrial laboratories.

The National Human Genome Research Institute (NHGRI) has participated in numerous trans-NIH efforts, including one on bioengineering research. The development of integrated concepts and tools for genomic research benefits from bioengineering research, methods and approaches. NHGRI supports bioengineering research through grants made in response to NHGRI program announcements and requests for application, and through NHGRI participation in trans-NIH bioengineering program announcements, such as the Bioengineering Research Grants (BRG) program and other Funding Opportunities that are listed below.

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Genome Technology Program Related Information

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Genome Technology Program Reports

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Genome Technology Program Policies

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Genome Technology Program Funding Opportunities

Nucleic Acid Sequencing

Novel Nucleic Acid Sequencing Technology Development (R21)
RFA-HG-15-031 [grants.nih.gov]
Application Due Date(s): October 27, 2015; July 14, 2016; June 15, 2017
Expiration Date: August 28, 2017

Novel Nucleic Acid Sequencing Technology Development (R01)
RFA-HG-15-032 [grants.nih.gov]
Application Due Date(s): October 27, 2015; July 14, 2016; June 15, 2017
Expiration Date: August 28, 2017

Novel Nucleic Acid Sequencing Technology Development (R43/R44)
RFA-HG-15-033 [grants.nih.gov]
Application Due Date(s): October 27, 2015; July 14, 2016; June 15, 2017
Expiration Date: August 28, 2017

Novel Nucleic Acid Sequencing Technology Development - Direct to Phase II (R44) New
RFA-HG-15-039 [grants.nih.gov]
Application Receipt Date: October 27, 2015; July 14, 2016; June 15, 2017
Expiration Date: August 28, 2017

  • Notice Clarifying Eligibility Criteria for RFA-HG-15-039 "Novel Nucleic Acid Sequencing Technology Development - Direct to Phase II (R44)" New
    NOT-HG-16-008 [grants.nih.gov]
     
Genomic Technology Development:

Novel Genomic Technology Development (R01) New
PAR-16-014 [grants.nih.gov]
Application Receipt Date(s): January 14, 2016; October 31, 2016; October 31, 2017
Expiration Date: January 12, 2018

Novel Genomic Technology Development (R21) New
PAR-16-015 [grants.nih.gov]
Application Receipt Date(s): January 14, 2016; October 31, 2016; October 31, 2017
Expiration Date: January 12, 2018

Novel Genomic Technology Development (R43/R44) New
PAR-16-016 [grants.nih.gov]
Application Receipt Date(s): January 14, 2016; October 31, 2016; October 31, 2017
Expiration Date: January 12, 2018

Novel Genomic Technology Development Direct to Phase II SBIR (R44) New
PAR-16-017 [grants.nih.gov]
Application Receipt Date(s): January 14, 2016; October 31, 2016
Expiration Date: January 12, 2017

Many other solicitations are appropriate means for submitting genomic technology development grant applications. Please see NHGRI's Funding Opportunities page at NHGRI Funding Opportunities

Expired Grant Solicitations

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Genome Technology Program Advanced Sequencing Technology Awards

In 2004, NHGRI initiated a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.

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Genome Technology Features

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Genome Technology Program Bibliography: Publications and Patents

NHGRI launched an ambitious program in 2004 to reduce the cost of full mammalian genome sequencing initially by 100-fold and subsequently by an additional 100-fold, aiming ultimately at about $1,000. Below, listed by Principal Investigator, are citations and links to many of the articles and patents resulting from this program and closely related research.

Genome Technology Program Publications and PatentsPDF file

Genome Technology Program Staff

Program Directors

Michael Smith, Ph.D.
E-mail: smithmw@mail.nih.gov

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Last Updated: October 31, 2016