Director's Report-Related Documents

New Seminar Series: Genomic Innovators

Historically Speaking Program Series

NHGRI Workshops at 2022 ASHG Meeting

Retirement of NIH Deputy Director Program Coordination, Planning, and Strategic Initiatives

New President’s Chief Advisor for Science and Technology & Director, White House Office of Science and Technology Policy

New Director, Advanced Research Projects Agency for Health (ARPA-H)

New Director, National Cancer Institute

New NIH Acting Deputy Director for Intramural Research

New Director, NIH Office of Equity, Diversity, and Inclusion

NIH Data Management and Sharing Policy

Fiscal Year 2023 Appropriations

President Biden’s Fiscal Year 2023 Budget Request

House Appropriations Fiscal Year 2023 Labor-HHS Bill

Senate Appropriations Fiscal Year 2023 Labor-HHS Bill

Mourning the Loss of Leon Rosenberg

New Leadership, American Society of Human Genetics

Time 100 Most Influential People of 2022

Kavli Prize in Neuroscience

New World Health Organization Science Council Report

Human Genome Reference Program (HGRP)

HGRP Program Website

HGRP Consortium Website

Ting et al. – “The Human Pangenome Project: A Global Resource to Map Genomic Diversity”

Liao et al. – “A Draft Human Pangenome Reference”

Molecular Phenotypes of Null Alleles in Cells (MorPhiC)

MorPhiC Program Website

RFA-HG-21-019 - Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase I: Data Analysis and Validation Centers (U01)

MorPhiC Email Contact

Non-Human Primate (NHP) Developmental Genotype-Tissue Expression Project (dGTEx)

Capturing RNA Sequence and Transcript Diversity, from Technology Innovation to Clinical Application Workshop

Electronic Medical Records and Genomics (eMERGE) Network

eMERGE Program Website

Khan et al. – “Genome-Wide Polygenic Score to Predict Chronic Kidney Disease Across Ancestries”

Dikilitas et al. – “Use of Polygenic Risk Scores for Coronary Heart Disease in Ancestrally Diverse Populations”

Multi-Omics for Health and Disease

Multi-Omics for Health and Disease Concept Clearance

RFA-HG-22-008 - Multi-Omics for Health and Disease - Disease Study Sites (U01)

RFA-HG-22-009 - Multi-Omics for Health and Disease - 'Omics Production Centers (U01)

RFA-HG-22-010 - Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01)

Clinical Genome Resource (ClinGen) 

ClinGen Website

Gene Curation Collection (GenCC)

DiStefano et al. – “The Gene Curation Coalition: A Global Effort to Harmonize Gene-Disease evidence Resources”

Genomic Medicine XIV: Genomic Learning Healthcare Systems (gLHS)

Technology Development Program

Technology Development Program Website

2022 NHGRI Advanced Genomic Technology Development Meeting 

Technology Development Coordinating Center (TDCC) Website

RFA-HG-21-006 - Transformative Nucleic Acid Sequencing Technology Innovation and Early Development (R01)

RFA-HG-21-007 - Transformative Nucleic Acid Sequencing Technology Innovation and Early Development (R21)

RFA-HG-21-008 - Transformative Nucleic Acid Sequencing Technology Innovation and Early Development (R43/R44)

NOT-HG-21-018 - Advancing Genomic Technology Development for Research and Clinical Application

Small Business Program

NHGRI Small Business Program Website

PA-20-025 - Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42)

PA-20-047 - Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)

NOT-EB-21-001 - Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health [Notice of Special Interest (NOSI)]

NOT-HG-21-038 - Genomics Education Interactive Digital Media Resources (SBIR/STTR) Notice of Special Interest (NOSI)

PA-22-176 - PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications [Parent SBIR (R43/R44) Clinical Trial Not Allowed]

PA-22-177 - PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications [Parent SBIR (R43/R44) Clinical Trial Required]

PA-22-178 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications [Parent STTR (R41/R42) Clinical Trial Not Allowed]

PA-22-179 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications [Parent STTR (R41/R42) Clinical Trial Required]

Training, Career Development, and Diversity Programs

NHGRI Training and Career Development Program Website

PAR-21-143 - NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00)

PA-21-071 - Research Supplements to Promote Diversity in Health-Related Research

NOT-HG-22-030 - Notice of Intent to Publish a Funding Opportunity Announcement for Diversity Centers for Genome Research (U54)

NOT-HG-22-031 - Notice of Intent to Publish a Funding Opportunity Announcement for Diversity Centers for Genome Research (UG3/UH3)

GREAT Program Frequently Asked Questions

RFA-HG-22-004 - Genome Research Experiences to Attract Talented Undergraduates into Genomic Fields to Enhance Diversity (GREAT) (R25)

RFA-HG-22-001 - Supporting Talented Early Career Researchers in Genomics (R01)

RFA-HG-21-041 - New Investigators to Promote Workforce Diversity in Genomics, Bioinformatics, or Bioengineering and Biomedical Imaging Research (R01)

Extramural Investigator-Initiated Highlights

Smith et al. – “Enrichment Analyses Identify Shared Associations for 25 Quantitative Traits in Over 600,000 Individuals from Seven Diverse Ancestries”

Callahan et al. – “Influence of Genetic Information on Neonatologists' Decisions: A Psychological Experiment”

Vaishnav et al. – “The Evolution, Evolvability and Engineering of Gene Regulatory DNA”

NHGRI Review of Requests for Applications with >$500K Direct Costs

NHGRI Program Guidance

NOT-OD-02-004 - NIH Policy on the Acceptance for Review of Unsolicited Applications over $500,000 or More in Direct Costs

NOT-HG-22-033 - NHGRI implementation of NIH Policy on Acceptance for Review of Applications Requesting $500,000 or More in Direct Costs in a Single Year

Scientific Areas of Emphasis and Extramural Research Program Contacts Website

Scientific Areas of Emphasis Overview

Scientific Areas of Emphasis Search

Knockout Mouse Phenotyping Project (KOMP2)

KOMP2 Program Website

Mutant Mouse Resource and Research Centers Repository Website

International Mouse Phenotyping Consortium Website

Fell et al. – “NIH Renews Knockout Mouse Project for 3rd Time”

Human Heredity & Health in Africa (H3Africa)

Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa)

DSI-Africa Website

DSI-Africa Funding Opportunities

Bridge to Artificial Intelligence (Bridge2AI)

NIH Cloud Platform Interoperability (NCPI) 

NCPI Portal

NCPI Research Opportunity Announcement

NIH Common Fund

Office of Strategic Coordination

NOT-RM-22-016 - Soliciting Ideas for New NIH Common Fund Programs

Genomics and the Media

NHGRI History of Genomics Program

NHGRI History of Genomics Program Website

NHGRI News Feature

The History of Genomics Told Through Machine Learning Lecture

Human Genome Project Fact Sheet

Irreducible Subjects: Disability and Genomics in the Past, Present, and Future Symposium

2022 Virtual Short Course in Genomics

NHGRI Genomic Education Resources (GenomeEd)

Healthcare Professionals’ Genomics Education Week

New Member, American Philosophical Society

NHGRI Intramural Research Highlights

Barrios et al. – “Patagonian Sheepdog: Genomic Analyses Trace the Footprints of Extinct UK Herding Dogs to South America”

Head et al. – “Aberrant Methylmalonylation Underlies Methylmalonic Acidemia and Is Attenuated by an Engineered Sirtuin”

Awotoye et al. – “Whole-Genome Sequencing Reveals De-Novo Mutations Associated with Nonsyndromic Cleft Lip/Palate”

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